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Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity

Calcineurin inhibitors are powerful immunosuppressants that revolutionized organ transplantation. However, non-immune effects of the calcineurin inhibitor, such as cyclosporine A (CsA), have significantly hindered their use. Specifically, nephrotoxicity, which is associated with tubulointerstitial f...

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Detalles Bibliográficos
Autores principales: Gooch, Jennifer L., King, Clayton, Francis, Cynthia E., Garcia, Paul S., Bai, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393575/
https://www.ncbi.nlm.nih.gov/pubmed/28414804
http://dx.doi.org/10.1371/journal.pone.0175242