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Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity
Calcineurin inhibitors are powerful immunosuppressants that revolutionized organ transplantation. However, non-immune effects of the calcineurin inhibitor, such as cyclosporine A (CsA), have significantly hindered their use. Specifically, nephrotoxicity, which is associated with tubulointerstitial f...
Autores principales: | Gooch, Jennifer L., King, Clayton, Francis, Cynthia E., Garcia, Paul S., Bai, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393575/ https://www.ncbi.nlm.nih.gov/pubmed/28414804 http://dx.doi.org/10.1371/journal.pone.0175242 |
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