Enhanced offspring predisposition to steatohepatitis with maternal high-fat diet is associated with epigenetic and microbiome alterations

OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is an important co-morbidity associated with obesity and a precursor to steatohepatitis. However, the contributions of gestational and early life influences on development of NAFLD and NASH remain poorly appreciated. METHODS: Two independent studi...

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Detalles Bibliográficos
Autores principales: Wankhade, Umesh D., Zhong, Ying, Kang, Ping, Alfaro, Maria, Chintapalli, Sree V., Thakali, Keshari M., Shankar, Kartik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393586/
https://www.ncbi.nlm.nih.gov/pubmed/28414763
http://dx.doi.org/10.1371/journal.pone.0175675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393586/
https://www.ncbi.nlm.nih.gov/pubmed/28414763
http://dx.doi.org/10.1371/journal.pone.0175675

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