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Enhanced offspring predisposition to steatohepatitis with maternal high-fat diet is associated with epigenetic and microbiome alterations
OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is an important co-morbidity associated with obesity and a precursor to steatohepatitis. However, the contributions of gestational and early life influences on development of NAFLD and NASH remain poorly appreciated. METHODS: Two independent studi...
Autores principales: | Wankhade, Umesh D., Zhong, Ying, Kang, Ping, Alfaro, Maria, Chintapalli, Sree V., Thakali, Keshari M., Shankar, Kartik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393586/ https://www.ncbi.nlm.nih.gov/pubmed/28414763 http://dx.doi.org/10.1371/journal.pone.0175675 |
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