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Probing the canonicity of the Wnt/Wingless signaling pathway

The hallmark of canonical Wnt signaling is the transcriptional induction of Wnt target genes by the beta-catenin/TCF complex. Several studies have proposed alternative interaction partners for beta-catenin or TCF, but the relevance of potential bifurcations in the distal Wnt pathway remains unclear....

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Detalles Bibliográficos
Autores principales: Franz, Alexandra, Shlyueva, Daria, Brunner, Erich, Stark, Alexander, Basler, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393890/
https://www.ncbi.nlm.nih.gov/pubmed/28369070
http://dx.doi.org/10.1371/journal.pgen.1006700