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Disrupting the cortical actin cytoskeleton points to two distinct mechanisms of yeast [PSI(+)] prion formation
Mammalian and fungal prions arise de novo; however, the mechanism is poorly understood in molecular terms. One strong possibility is that oxidative damage to the non-prion form of a protein may be an important trigger influencing the formation of its heritable prion conformation. We have examined th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393896/ https://www.ncbi.nlm.nih.gov/pubmed/28369054 http://dx.doi.org/10.1371/journal.pgen.1006708 |