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Transient chromatin properties revealed by polymer models and stochastic simulations constructed from Chromosomal Capture data
Chromatin organization can be probed by Chromosomal Capture (5C) data, from which the encounter probability (EP) between genomic sites is presented in a large matrix. This matrix is averaged over a large cell population, revealing diagonal blocks called Topological Associating Domains (TADs) that re...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393903/ https://www.ncbi.nlm.nih.gov/pubmed/28369076 http://dx.doi.org/10.1371/journal.pcbi.1005469 |