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VirF Relieves the Transcriptional Attenuation of the Virulence Gene icsA of Shigella flexneri Affecting the icsA mRNA–RnaG Complex Formation

VirF is the master activator of virulence genes of Shigella and its expression is required for the invasion of the human intestinal mucosa by pathogenic bacteria. VirF was shown to directly activate the transcription of virB and icsA, which encode two essential proteins involved in the pathogenicity...

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Detalles Bibliográficos
Autores principales: Giangrossi, Mara, Giuliodori, Anna M., Tran, Chi N., Amici, Augusto, Marchini, Cristina, Falconi, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394118/
https://www.ncbi.nlm.nih.gov/pubmed/28458662
http://dx.doi.org/10.3389/fmicb.2017.00650