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Genetic and Epigenetic Intra-tumour Heterogeneity in Colorectal Cancer

INTRODUCTION: Colorectal cancer (CRC) is a highly heterogeneous disease, with pathologically similar cancers having completely different responses to treatment and patient survival. Intra-tumour heterogeneity (defined as distinct morphological and phenotypic differences) has recently been demonstrat...

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Detalles Bibliográficos
Autores principales: Jones, Huw Geraint, Jenkins, Gareth, Williams, Namor, Griffiths, Paul, Chambers, Phil, Beynon, John, Harris, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394146/
https://www.ncbi.nlm.nih.gov/pubmed/28097409
http://dx.doi.org/10.1007/s00268-016-3860-z