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Genetic and Epigenetic Intra-tumour Heterogeneity in Colorectal Cancer
INTRODUCTION: Colorectal cancer (CRC) is a highly heterogeneous disease, with pathologically similar cancers having completely different responses to treatment and patient survival. Intra-tumour heterogeneity (defined as distinct morphological and phenotypic differences) has recently been demonstrat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394146/ https://www.ncbi.nlm.nih.gov/pubmed/28097409 http://dx.doi.org/10.1007/s00268-016-3860-z |