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Spared Nerve Injury Increases the Expression of Microglia M1 Markers in the Prefrontal Cortex of Rats and Provokes Depression-Like Behaviors

Pain and depression are frequently co-existent in clinical practice, yet the underlying mechanisms remain largely to be determined. Microglia activation and subsequent pro-inflammatory responses play a crucial role in the development of neuropathic pain and depression. The process of microglia polar...

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Detalles Bibliográficos
Autores principales: Xu, Ning, Tang, Xiao-Hui, Pan, Wei, Xie, Ze-Min, Zhang, Guang-Fen, Ji, Mu-Huo, Yang, Jian-Jun, Zhou, Mai-Tao, Zhou, Zhi-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394168/
https://www.ncbi.nlm.nih.gov/pubmed/28458629
http://dx.doi.org/10.3389/fnins.2017.00209