Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ

Low-density lipoprotein receptor-related protein 1 (LRP1) regulates lipid and glucose metabolism in liver and adipose tissue. It is also involved in central nervous system regulation of food intake and leptin signalling. Here we demonstrate that endothelial Lrp1 regulates systemic energy homeostasis...

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Detalles Bibliográficos
Autores principales: Mao, Hua, Lockyer, Pamela, Li, Luge, Ballantyne, Christie M., Patterson, Cam, Xie, Liang, Pi, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394236/
https://www.ncbi.nlm.nih.gov/pubmed/28393867
http://dx.doi.org/10.1038/ncomms14960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394236/
https://www.ncbi.nlm.nih.gov/pubmed/28393867
http://dx.doi.org/10.1038/ncomms14960

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