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Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ
Low-density lipoprotein receptor-related protein 1 (LRP1) regulates lipid and glucose metabolism in liver and adipose tissue. It is also involved in central nervous system regulation of food intake and leptin signalling. Here we demonstrate that endothelial Lrp1 regulates systemic energy homeostasis...
Autores principales: | Mao, Hua, Lockyer, Pamela, Li, Luge, Ballantyne, Christie M., Patterson, Cam, Xie, Liang, Pi, Xinchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394236/ https://www.ncbi.nlm.nih.gov/pubmed/28393867 http://dx.doi.org/10.1038/ncomms14960 |
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