Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis

The metastatic organotropism has been one of the cancer's greatest mysteries since the ‘seed and soil' hypothesis. Although the role of EGFR in cancer cells is well studied, the effects of secreted EGFR transported by exosomes are less understood. Here we show that EGFR in exosomes secrete...

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Detalles Bibliográficos
Autores principales: Zhang, Haiyang, Deng, Ting, Liu, Rui, Bai, Ming, Zhou, Likun, Wang, Xia, Li, Shuang, Wang, Xinyi, Yang, Haiou, Li, Jialu, Ning, Tao, Huang, Dingzhi, Li, Hongli, Zhang, Le, Ying, Guoguang, Ba, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394240/
https://www.ncbi.nlm.nih.gov/pubmed/28393839
http://dx.doi.org/10.1038/ncomms15016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394240/
https://www.ncbi.nlm.nih.gov/pubmed/28393839
http://dx.doi.org/10.1038/ncomms15016

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