Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models

Bacteria can be genetically engineered to kill specific pathogens or inhibit their virulence. We previously developed a synthetic genetic system that allows a laboratory strain of Escherichia coli to sense and kill Pseudomonas aeruginosa in vitro. Here, we generate a modified version of the system,...

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Detalles Bibliográficos
Autores principales: Hwang, In Young, Koh, Elvin, Wong, Adison, March, John C., Bentley, William E., Lee, Yung Seng, Chang, Matthew Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394271/
https://www.ncbi.nlm.nih.gov/pubmed/28398304
http://dx.doi.org/10.1038/ncomms15028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394271/
https://www.ncbi.nlm.nih.gov/pubmed/28398304
http://dx.doi.org/10.1038/ncomms15028

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