Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP Signaling

Hundreds of hormones and ligands stimulate cyclic AMP (cAMP) signaling in different tissues through the activation of G-protein-coupled receptors (GPCRs). Although the functions and individual effectors of cAMP signaling are well characterized in many tissues, pleiotropic effects of GPCR agonists li...

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Detalles Bibliográficos
Autores principales: Akhmedov, Dmitry, Mendoza-Rodriguez, Maria G., Rajendran, Kavitha, Rossi, Mario, Wess, Jürgen, Berdeaux, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394278/
https://www.ncbi.nlm.nih.gov/pubmed/28167604
http://dx.doi.org/10.1128/MCB.00584-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394278/
https://www.ncbi.nlm.nih.gov/pubmed/28167604
http://dx.doi.org/10.1128/MCB.00584-16

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