Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration

Directed migration by contact guidance is a poorly understood yet vital phenomenon, particularly for carcinoma cell invasion on aligned collagen fibres. We demonstrate that for single cells, aligned architectures providing contact guidance cues induce constrained focal adhesion maturation and associ...

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Detalles Bibliográficos
Autores principales: Ray, Arja, Lee, Oscar, Win, Zaw, Edwards, Rachel M., Alford, Patrick W., Kim, Deok-Ho, Provenzano, Paolo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394287/
https://www.ncbi.nlm.nih.gov/pubmed/28401884
http://dx.doi.org/10.1038/ncomms14923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394287/
https://www.ncbi.nlm.nih.gov/pubmed/28401884
http://dx.doi.org/10.1038/ncomms14923

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