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Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer
Allosteric modulators that are targeting the calcium-sensing receptor (CaSR) hold great therapeutic potential, and elucidating the molecular basis for modulation would thus benefit the development of novel therapeutics. In the present study, we aimed at investigating the mechanism of allosteric modu...
Autores principales: | Jacobsen, Stine Engesgaard, Gether, Ulrik, Bräuner-Osborne, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394417/ https://www.ncbi.nlm.nih.gov/pubmed/28417952 http://dx.doi.org/10.1038/srep46355 |
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