A New Approach to Evaluating Aberrant DNA Methylation Profiles in Hepatocellular Carcinoma as Potential Biomarkers

Hypermethylation of CpG islands in the promoter region of tumor suppressor genes (TSGs) and their subsequent silencing is thought to be one of the main mechanisms of carcinogenesis. MBD2b enrichment coupled with a NimbleGen array was applied to examine the genome-wide CpG island methylation profile...

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Detalles Bibliográficos
Autores principales: Yang, Yuan, Zhao, Linghao, Huang, Bo, Hou, Guojun, Zhou, Beibei, Qian, Jin, Yuan, Shengxian, Xiao, Huasheng, Li, Minghui, Zhou, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394454/
https://www.ncbi.nlm.nih.gov/pubmed/28418032
http://dx.doi.org/10.1038/srep46533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394454/
https://www.ncbi.nlm.nih.gov/pubmed/28418032
http://dx.doi.org/10.1038/srep46533

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