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The BMP2 nuclear variant, nBMP2, is expressed in mouse hippocampus and impacts memory

The novel nuclear protein nBMP2 is synthesized from the BMP2 gene by translational initiation at an alternative start codon. We generated a targeted mutant mouse, nBmp2NLS(tm), in which the nuclear localization signal (NLS) was inactivated to prevent nuclear translocation of nBMP2 while still allowi...

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Detalles Bibliográficos
Autores principales: Cordner, Ryan D., Friend, Lindsey N., Mayo, Jaime L., Badgley, Corinne, Wallmann, Andrew, Stallings, Conrad N., Young, Peter L., Miles, Darla R., Edwards, Jeffrey G., Bridgewater, Laura C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394474/
https://www.ncbi.nlm.nih.gov/pubmed/28418030
http://dx.doi.org/10.1038/srep46464