Cargando…
The BMP2 nuclear variant, nBMP2, is expressed in mouse hippocampus and impacts memory
The novel nuclear protein nBMP2 is synthesized from the BMP2 gene by translational initiation at an alternative start codon. We generated a targeted mutant mouse, nBmp2NLS(tm), in which the nuclear localization signal (NLS) was inactivated to prevent nuclear translocation of nBMP2 while still allowi...
Autores principales: | Cordner, Ryan D., Friend, Lindsey N., Mayo, Jaime L., Badgley, Corinne, Wallmann, Andrew, Stallings, Conrad N., Young, Peter L., Miles, Darla R., Edwards, Jeffrey G., Bridgewater, Laura C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394474/ https://www.ncbi.nlm.nih.gov/pubmed/28418030 http://dx.doi.org/10.1038/srep46464 |
Ejemplares similares
-
The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response
por: Tellez Freitas, Claudia M., et al.
Publicado: (2019) -
A Novel Bone Morphogenetic Protein 2 Mutant Mouse, nBmp2NLS(tm), Displays Impaired Intracellular Ca(2+) Handling in Skeletal Muscle
por: Bridgewater, Laura C., et al.
Publicado: (2013) -
BMP7 functions predominantly as a heterodimer with BMP2 or BMP4 during mammalian embryogenesis
por: Kim, Hyung-Seok, et al.
Publicado: (2019) -
Genetic Analysis of the Roles of BMP2, BMP4, and BMP7 in Limb Patterning and Skeletogenesis
por: Bandyopadhyay, Amitabha, et al.
Publicado: (2006) -
Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers
por: Gipson, Gregory R., et al.
Publicado: (2023)