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Notch Signaling in T Helper Cell Subsets: Instructor or Unbiased Amplifier?
For protection against pathogens, it is essential that naïve CD4(+) T cells differentiate into specific effector T helper (Th) cell subsets following activation by antigen presented by dendritic cells (DCs). Next to T cell receptor and cytokine signals, membrane-bound Notch ligands have an important...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394483/ https://www.ncbi.nlm.nih.gov/pubmed/28458667 http://dx.doi.org/10.3389/fimmu.2017.00419 |