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Cyclic GMP-dependent protein kinase-I localized in nociceptors modulates nociceptive cortical neuronal activity and pain hypersensitivity

Chronic pain represents a frequent and poorly understood public health issue. Numerous studies have documented the key significance of plastic changes along the somatosensory pain pathways in chronic pain states. Our recent study demonstrated that the cGMP-dependent protein kinase I (PKG-I) specific...

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Detalles Bibliográficos
Autores principales: Gangadharan, Vijayan, Wang, Xu, Luo, Ceng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394618/
https://www.ncbi.nlm.nih.gov/pubmed/28326941
http://dx.doi.org/10.1177/1744806917701743