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The Cac2 subunit is essential for productive histone binding and nucleosome assembly in CAF-1
Nucleosome assembly following DNA replication controls epigenome maintenance and genome integrity. Chromatin assembly factor 1 (CAF-1) is the histone chaperone responsible for histone (H3-H4)(2) deposition following DNA synthesis. Structural and functional details for this chaperone complex and its...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394680/ https://www.ncbi.nlm.nih.gov/pubmed/28418026 http://dx.doi.org/10.1038/srep46274 |