Cargando…

The Cac2 subunit is essential for productive histone binding and nucleosome assembly in CAF-1

Nucleosome assembly following DNA replication controls epigenome maintenance and genome integrity. Chromatin assembly factor 1 (CAF-1) is the histone chaperone responsible for histone (H3-H4)(2) deposition following DNA synthesis. Structural and functional details for this chaperone complex and its...

Descripción completa

Detalles Bibliográficos
Autores principales: Mattiroli, Francesca, Gu, Yajie, Balsbaugh, Jeremy L., Ahn, Natalie G., Luger, Karolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394680/
https://www.ncbi.nlm.nih.gov/pubmed/28418026
http://dx.doi.org/10.1038/srep46274