Recombinant Adeno-Associated Virus-mediated rescue of function in a mouse model of Dopamine Transporter Deficiency Syndrome

Dopamine Transporter Deficiency Syndrome (DTDS) is a rare autosomal recessive disorder caused by loss-of-function mutations in dopamine transporter (DAT) gene, leading to severe neurological disabilities in children and adults. DAT-Knockout (DAT-KO) mouse is currently the best animal model for this...

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Detalles Bibliográficos
Autores principales: Illiano, P., Bass, C.E., Fichera, L., Mus, L., Budygin, E.A., Sotnikova, T.D., Leo, D., Espinoza, S., Gainetdinov, R.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394687/
https://www.ncbi.nlm.nih.gov/pubmed/28417953
http://dx.doi.org/10.1038/srep46280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394687/
https://www.ncbi.nlm.nih.gov/pubmed/28417953
http://dx.doi.org/10.1038/srep46280

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