CenpH regulates meiotic G2/M transition by modulating the APC/C(Cdh1)-cyclin B1 pathway in oocytes

Meiotic resumption (G2/M transition) and progression through meiosis I (MI) are two key stages for producing fertilization-competent eggs. Here, we report that CenpH, a component of the kinetochore inner plate, is responsible for G2/M transition in meiotic mouse oocytes. Depletion of CenpH by morpho...

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Detalles Bibliográficos
Autores principales: Zhang, Teng, Zhou, Yang, Li, Li, Wang, Zhen-Bo, Shen, Wei, Schatten, Heide, Sun, Qing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394759/
https://www.ncbi.nlm.nih.gov/pubmed/27993978
http://dx.doi.org/10.1242/dev.141135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394759/
https://www.ncbi.nlm.nih.gov/pubmed/27993978
http://dx.doi.org/10.1242/dev.141135

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