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CenpH regulates meiotic G2/M transition by modulating the APC/C(Cdh1)-cyclin B1 pathway in oocytes
Meiotic resumption (G2/M transition) and progression through meiosis I (MI) are two key stages for producing fertilization-competent eggs. Here, we report that CenpH, a component of the kinetochore inner plate, is responsible for G2/M transition in meiotic mouse oocytes. Depletion of CenpH by morpho...
Autores principales: | Zhang, Teng, Zhou, Yang, Li, Li, Wang, Zhen-Bo, Shen, Wei, Schatten, Heide, Sun, Qing-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394759/ https://www.ncbi.nlm.nih.gov/pubmed/27993978 http://dx.doi.org/10.1242/dev.141135 |
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