The Isl1-Lhx3 Complex Promotes Motor Neuron Specification by Activating Transcriptional Pathways that Enhance Its Own Expression and Formation

Motor neuron (MN) progenitor cells rapidly induce high expression of the transcription factors Islet-1 (Isl1), LIM-homeobox 3 (Lhx3), and the transcriptional regulator LMO4, as they differentiate. While these factors are critical for MN specification, the mechanisms regulating their precise temporal...

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Detalles Bibliográficos
Autores principales: Erb, Madalynn, Lee, Bora, Yeon Seo, So, Lee, Jae W., Lee, Seunghee, Lee, Soo-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394944/
https://www.ncbi.nlm.nih.gov/pubmed/28451636
http://dx.doi.org/10.1523/ENEURO.0349-16.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394944/
https://www.ncbi.nlm.nih.gov/pubmed/28451636
http://dx.doi.org/10.1523/ENEURO.0349-16.2017

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