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T cells in chronic lymphocytic leukemia display dysregulated expression of immune checkpoints and activation markers
Chronic lymphocytic leukemia is characterized by impaired immune functions largely due to profound T-cell defects. T-cell functions also depend on co-signaling receptors, inhibitory or stimulatory, known as immune checkpoints, including cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) and progra...
Autores principales: | Palma, Marzia, Gentilcore, Giusy, Heimersson, Kia, Mozaffari, Fariba, Näsman-Glaser, Barbro, Young, Emma, Rosenquist, Richard, Hansson, Lotta, Österborg, Anders, Mellstedt, Håkan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394965/ https://www.ncbi.nlm.nih.gov/pubmed/27927767 http://dx.doi.org/10.3324/haematol.2016.151100 |
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