CEBPA–double-mutated acute myeloid leukemia displays a unique phenotypic profile: a reliable screening method and insight into biological features

Mutations in CCAAT/enhancer binding protein α (CEBPA) occur in 5–10% of cases of acute myeloid leukemia. CEBPA-double-mutated cases usually bear biallelic N- and C-terminal mutations and are associated with a favorable clinical outcome. Identification of CEBPA mutants is challenging because of the v...

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Detalles Bibliográficos
Autores principales: Mannelli, Francesco, Ponziani, Vanessa, Bencini, Sara, Bonetti, Maria Ida, Benelli, Matteo, Cutini, Ilaria, Gianfaldoni, Giacomo, Scappini, Barbara, Pancani, Fabiana, Piccini, Matteo, Rondelli, Tommaso, Caporale, Roberto, Gelli, Anna Maria Grazia, Peruzzi, Benedetta, Chiarini, Marco, Borlenghi, Erika, Spinelli, Orietta, Giupponi, Damiano, Zanghì, Pamela, Bassan, Renato, Rambaldi, Alessandro, Rossi, Giuseppe, Bosi, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394975/
https://www.ncbi.nlm.nih.gov/pubmed/28250006
http://dx.doi.org/10.3324/haematol.2016.151910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394975/
https://www.ncbi.nlm.nih.gov/pubmed/28250006
http://dx.doi.org/10.3324/haematol.2016.151910

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