PiggyBac Transposon-Mediated Mutagenesis in Rats Reveals a Crucial Role of Bbx in Growth and Male Fertility

Bobby sox homolog (Bbx) is an evolutionally conserved gene, but its biological function remains elusive. Here, we characterized defects of Bbx mutant rats that were created by PiggyBac-mediated insertional mutagenesis. Smaller body size and male infertility were the two major phenotypes of homozygou...

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Detalles Bibliográficos
Autores principales: Wang, Chieh-Ying, Tang, Ming-Chu, Chang, Wen-Chi, Furushima, Kenryo, Jang, Chuan-Wei, Behringer, Richard R, Chen, Chun-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394979/
https://www.ncbi.nlm.nih.gov/pubmed/27465138
http://dx.doi.org/10.1095/biolreprod.116.141739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394979/
https://www.ncbi.nlm.nih.gov/pubmed/27465138
http://dx.doi.org/10.1095/biolreprod.116.141739

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