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Uterotonic Neuromedin U Receptor 2 and Its Ligands Are Upregulated by Inflammation in Mice and Humans, and Elicit Preterm Birth

Uterine labor requires the conversion of a quiescent (propregnancy) uterus into an activated (prolabor) uterus, with increased sensitivity to endogenous uterotonic molecules. This activation is induced by stressors, particularly inflammation in term and preterm labor. Neuromedin U (NmU) is a neurope...

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Detalles Bibliográficos
Autores principales: Nadeau-Vallée, Mathieu, Boudreault, Amarilys, Leimert, Kelycia, Hou, Xin, Obari, Dima, Madaan, Ankush, Rouget, Raphaël, Zhu, Tang, Belarbi, Lydia, Brien, Marie-Ève, Beaudry-Richard, Alexandra, Olson, David M., Girard, Sylvie, Chemtob, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394981/
https://www.ncbi.nlm.nih.gov/pubmed/27512149
http://dx.doi.org/10.1095/biolreprod.116.140905