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Dual role of IL-21 in megakaryopoiesis and platelet homeostasis

Gene profiling studies have indicated that in vitro differentiated human megakaryocytes express the receptor for IL-21 (IL-21R), an immunostimulatory cytokine associated with inflammatory disorders and currently under evaluation in cancer therapy. The aim of this study was to investigate whether IL-...

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Detalles Bibliográficos
Autores principales: Benbarche, Salima, Strassel, Catherine, Angénieux, Catherine, Mallo, Léa, Freund, Monique, Gachet, Christian, Lanza, François, de la Salle, Henri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395104/
https://www.ncbi.nlm.nih.gov/pubmed/28057742
http://dx.doi.org/10.3324/haematol.2016.143958