Efferocytosis is impaired in Gaucher macrophages

Gaucher disease, the inherited deficiency of lysosomal glucocerebrosidase, is characterized by the presence of glucosylceramide-laden macrophages resulting from impaired digestion of aged erythrocytes or apoptotic leukocytes. Studies of macrophages from patients with type 1 Gaucher disease with geno...

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Detalles Bibliográficos
Autores principales: Aflaki, Elma, Borger, Daniel K., Grey, Richard J., Kirby, Martha, Anderson, Stacie, Lopez, Grisel, Sidransky, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395106/
https://www.ncbi.nlm.nih.gov/pubmed/28011901
http://dx.doi.org/10.3324/haematol.2016.155093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395106/
https://www.ncbi.nlm.nih.gov/pubmed/28011901
http://dx.doi.org/10.3324/haematol.2016.155093

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