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Efferocytosis is impaired in Gaucher macrophages
Gaucher disease, the inherited deficiency of lysosomal glucocerebrosidase, is characterized by the presence of glucosylceramide-laden macrophages resulting from impaired digestion of aged erythrocytes or apoptotic leukocytes. Studies of macrophages from patients with type 1 Gaucher disease with geno...
Autores principales: | Aflaki, Elma, Borger, Daniel K., Grey, Richard J., Kirby, Martha, Anderson, Stacie, Lopez, Grisel, Sidransky, Ellen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395106/ https://www.ncbi.nlm.nih.gov/pubmed/28011901 http://dx.doi.org/10.3324/haematol.2016.155093 |
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