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CD244 maintains the proliferation ability of leukemia initiating cells through SHP-2/p27(kip1) signaling

Targeting leukemia initiating cells is considered to be an effective way to cure leukemia, for which it is critical to identify novel therapeutic targets. Herein, we demonstrate that CD244, which was initially reported as a key regulator for natural killer cells, is highly expressed on both mouse an...

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Detalles Bibliográficos
Autores principales: Zhang, Feifei, Liu, Xiaoye, Chen, Chiqi, Zhu, Jun, Yu, Zhuo, Xie, Jingjing, Xie, Li, Bai, Haitao, Zhang, Yaping, Fang, Xia, Gu, Hao, Wang, Chun, Weng, Wei, Zhang, Cheng Cheng, Chen, Guo-Qiang, Liang, Aibing, Zheng, Junke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395111/
https://www.ncbi.nlm.nih.gov/pubmed/28126968
http://dx.doi.org/10.3324/haematol.2016.151555