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Multidrug-resistant bacteria compensate for the epistasis between resistances

Mutations conferring resistance to antibiotics are typically costly in the absence of the drug, but bacteria can reduce this cost by acquiring compensatory mutations. Thus, the rate of acquisition of compensatory mutations and their effects are key for the maintenance and dissemination of antibiotic...

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Detalles Bibliográficos
Autores principales: Moura de Sousa, Jorge, Balbontín, Roberto, Durão, Paulo, Gordo, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395140/
https://www.ncbi.nlm.nih.gov/pubmed/28419091
http://dx.doi.org/10.1371/journal.pbio.2001741