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Multidrug-resistant bacteria compensate for the epistasis between resistances
Mutations conferring resistance to antibiotics are typically costly in the absence of the drug, but bacteria can reduce this cost by acquiring compensatory mutations. Thus, the rate of acquisition of compensatory mutations and their effects are key for the maintenance and dissemination of antibiotic...
Autores principales: | Moura de Sousa, Jorge, Balbontín, Roberto, Durão, Paulo, Gordo, Isabel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395140/ https://www.ncbi.nlm.nih.gov/pubmed/28419091 http://dx.doi.org/10.1371/journal.pbio.2001741 |
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