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Stepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritis

Identification of the structure-function relationship of heparin, particularly between 2-O-, 6-O-, and N-sulfation and its anticoagulant or anti-inflammatory activities, is critical in order to evaluate the biological effects of heparin, especially in conjunction with modifications for oral formulat...

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Detalles Bibliográficos
Autores principales: Al Faruque, Hasan, Kang, Jin Hee, Hwang, Seung Rim, Sung, Shijin, Alam, Md. Mahmudul, Sa, Keum Hee, Nam, Eon Jeong, Byun, Young Ro, Kang, Young Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395217/
https://www.ncbi.nlm.nih.gov/pubmed/28419144
http://dx.doi.org/10.1371/journal.pone.0176110