Population pharmacokinetic modelling of rupatadine solution in 6–11 year olds and optimisation of the experimental design in younger children

AIMS: To optimise a pharmacokinetic (PK) study design of rupatadine for 2–5 year olds by using a population PK model developed with data from a study in 6–11 year olds. The design optimisation was driven by the need to avoid children’s discomfort in the study. METHODS: PK data from 6–11 year olds wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Santamaría, Eva, Estévez, Javier Alejandro, Riba, Jordi, Izquierdo, Iñaki, Valle, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395227/
https://www.ncbi.nlm.nih.gov/pubmed/28419164
http://dx.doi.org/10.1371/journal.pone.0176091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395227/
https://www.ncbi.nlm.nih.gov/pubmed/28419164
http://dx.doi.org/10.1371/journal.pone.0176091

Ejemplares similares