Simultaneous administration of fluoxetine and simvastatin ameliorates lipid profile, improves brain level of neurotransmitters, and increases bioavailability of simvastatin

Simvastatin (STT), a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, is widely prescribed for dyslipidemia, whereas fluoxetine (FLX) is the first-choice drug for the treatment of depression and anxiety. A recent report suggests that selective serotonin reuptake inhibitors can interact wit...

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Detalles Bibliográficos
Autores principales: Al-Asmari, Abdulrahman K, Ullah, Zabih, Al Masoudi, Aqeel Salman, Ahmad, Ishtiaque
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395284/
https://www.ncbi.nlm.nih.gov/pubmed/28442937
http://dx.doi.org/10.2147/JEP.S128696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395284/
https://www.ncbi.nlm.nih.gov/pubmed/28442937
http://dx.doi.org/10.2147/JEP.S128696

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