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TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin

Resolution and formation of facultative heterochromatin is essential to development, reprogramming, and oncogenesis. The mechanisms underlying these changes are poorly understood due to the inability to study heterochromatin dynamics and structure in vivo. We devised an in vivo approach to investiga...

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Detalles Bibliográficos
Autores principales: Miller, Erik L., Hargreaves, Diana C., Kadoch, Cigall, Chang, Chiung-Ying, Calarco, Joseph P., Hodges, Courtney, Buenrostro, Jason D., Cui, Kairong, Greenleaf, William J., Zhao, Keji, Crabtree, Gerald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395302/
https://www.ncbi.nlm.nih.gov/pubmed/28250416
http://dx.doi.org/10.1038/nsmb.3384