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TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin
Resolution and formation of facultative heterochromatin is essential to development, reprogramming, and oncogenesis. The mechanisms underlying these changes are poorly understood due to the inability to study heterochromatin dynamics and structure in vivo. We devised an in vivo approach to investiga...
Autores principales: | Miller, Erik L., Hargreaves, Diana C., Kadoch, Cigall, Chang, Chiung-Ying, Calarco, Joseph P., Hodges, Courtney, Buenrostro, Jason D., Cui, Kairong, Greenleaf, William J., Zhao, Keji, Crabtree, Gerald R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395302/ https://www.ncbi.nlm.nih.gov/pubmed/28250416 http://dx.doi.org/10.1038/nsmb.3384 |
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