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Epigenetic landscapes reveal transcription factors regulating CD8(+) T cell differentiation

Dynamic changes in the expression of transcription factors (TFs) can influence specification of distinct CD8(+) T cell fates, but the observation of equivalent expression of TF among differentially-fated precursor cells suggests additional underlying mechanisms. Here, we profiled genome-wide histone...

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Detalles Bibliográficos
Autores principales: Yu, Bingfei, Zhang, Kai, Milner, J. Justin, Toma, Clara, Chen, Runqiang, Scott-Browne, James P., Pereira, Renata M., Crotty, Shane, Chang, John T., Pipkin, Matthew E., Wang, Wei, Goldrath, Ananda W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395420/
https://www.ncbi.nlm.nih.gov/pubmed/28288100
http://dx.doi.org/10.1038/ni.3706