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Adaptative evolution of the Vkorc1 gene in Mus musculus domesticus is influenced by the selective pressure of anticoagulant rodenticides

Anticoagulant rodenticides are commonly used to control rodent pests worldwide. They specifically inhibit the vitamin K epoxide reductase (VKORC1), which is an enzyme encoded by the Vkorc1 gene, involved in the recycling of vitamin K. Therefore, they prevent blood clotting. Numerous mutations of Vko...

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Detalles Bibliográficos
Autores principales: Goulois, Joffrey, Lambert, Véronique, Legros, Lionel, Benoit, Etienne, Lattard, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395456/
https://www.ncbi.nlm.nih.gov/pubmed/28428867
http://dx.doi.org/10.1002/ece3.2829