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Honokiol Alleviates Hypertrophic Scar by Targeting Transforming Growth Factor-β/Smad2/3 Signaling Pathway

Hypertrophic scar (HPS) presents as excessive extracellular matrix deposition and abnormal function of fibroblasts. However, there is no single satisfactory method to prevent HPS formation so far. Here, we found that honokiol (HKL), a natural compound isolated from Magnolia tree, had an inhibitory e...

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Detalles Bibliográficos
Autores principales: Zhao, Danyang, Wang, Yu, Du, Chao, Shan, Shengzhou, Zhang, Yifan, Du, Zijing, Han, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395562/
https://www.ncbi.nlm.nih.gov/pubmed/28469575
http://dx.doi.org/10.3389/fphar.2017.00206