Interference with Ca(2+)-Dependent Proteolysis Does Not Alter the Course of Muscle Wasting in Experimental Cancer Cachexia

Protein hypercatabolism significantly contributes to the onset and progression of muscle wasting in cancer cachexia. In this regard, a major role is played by the ATP-ubiquitin-proteasome-dependent pathway and by autophagy. However, little is known about the relevance of the Ca(2+)-dependent proteol...

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Detalles Bibliográficos
Autores principales: Pin, Fabrizio, Minero, Valerio G., Penna, Fabio, Muscaritoli, Maurizio, De Tullio, Roberta, Baccino, Francesco M., Costelli, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395607/
https://www.ncbi.nlm.nih.gov/pubmed/28469577
http://dx.doi.org/10.3389/fphys.2017.00213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395607/
https://www.ncbi.nlm.nih.gov/pubmed/28469577
http://dx.doi.org/10.3389/fphys.2017.00213

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