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Exosomes and the Prion Protein: More than One Truth

Exosomes are involved in the progression of neurodegenerative diseases. The cellular prion protein (PrP(C)) is highly expressed on exosomes. In neurodegenerative diseases, PrP(C) has at least two functions: It is the substrate for the generation of pathological prion protein (PrP(Sc)), a key player...

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Detalles Bibliográficos
Autores principales: Hartmann, Alexander, Muth, Christiane, Dabrowski, Oliver, Krasemann, Susanne, Glatzel, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395619/
https://www.ncbi.nlm.nih.gov/pubmed/28469550
http://dx.doi.org/10.3389/fnins.2017.00194