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mtDNA, Metastasis, and the Mitochondrial Unfolded Protein Response (UPR(mt))

While several studies have confirmed a link between mitochondrial DNA (mtDNA) mutations and cancer cell metastasis, much debate remains regarding the nature of the alternations in mtDNA leading to this effect. Meanwhile, the mitochondrial unfolded protein response (UPR(mt)) has gained much attention...

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Detalles Bibliográficos
Autores principales: Kenny, Timothy C., Germain, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395626/
https://www.ncbi.nlm.nih.gov/pubmed/28470001
http://dx.doi.org/10.3389/fcell.2017.00037