Synergistic Internal Ribosome Entry Site/MicroRNA-Based Approach for Flavivirus Attenuation and Live Vaccine Development

The recent emergence of Zika virus underscores the need for new strategies for a rapid development of safe flavivirus vaccines. Using another flavivirus (Langat virus [LGTV]) that belongs to the group of tick-borne flaviviruses as a model, we describe a dual strategy for virus attenuation which syne...

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Detalles Bibliográficos
Autores principales: Tsetsarkin, Konstantin A., Liu, Guangping, Volkova, Evgeniya, Pletnev, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395672/
https://www.ncbi.nlm.nih.gov/pubmed/28420742
http://dx.doi.org/10.1128/mBio.02326-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395672/
https://www.ncbi.nlm.nih.gov/pubmed/28420742
http://dx.doi.org/10.1128/mBio.02326-16

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